Testerone deficiency with high sex drive. I have a lot of these symptoms for low progesterone specifically acne, headaches, long cycles, hot flashes at night but def not weight gain. October 8, at I have PCOS and you gave me a protocol for coming off the pill which i did one month ago. I was planning on staying on therapy for a year, and then I would like to have another baby so pausing therapy is what I am planning on doing. Thank you in advance. November 11, at Within two days at least. I was so desperate yesterday I went to the store and bought an over the counter black cohosh menopause pill. Also higher estrogen lowers testosterone output. Great post and very informative regarding the link between fat and estrogen. Well, I had some cramping and brain fog on the 3rd day of my period so I decided to take 10 drops of progesterone mixed with my water. The same thing happened when I tried spiro clear skin but sick body.